Structure of DNA

I. Introduction

  • DNA (deoxyribonucleic acid) is a molecule that encodes the genetic information of all living organisms.
  • Discovered by James Watson and Francis Crick in 1953, it has become one of the most studied and important molecules in biology.

II. Chemical Composition

  • DNA is made up of four nitrogenous bases: adenine (A), cytosine (C), guanine (G), and thymine (T).
  • These bases are linked together by a sugar-phosphate backbone.
  • The sugar in DNA is deoxyribose and the phosphate group creates a bond between the sugar molecules.

III. Double Helix Structure

  • The most famous aspect of the DNA structure is its double helix shape, which resembles a twisted ladder.
  • The two strands of the DNA molecule run in opposite directions, with the nitrogenous bases forming the rungs of the ladder.
  • The hydrogen bonds between the nitrogenous bases hold the two strands together.
  • A base pair is formed by two nitrogenous bases, one from each strand, and the base pairing rules are A-T and C-G.

IV. Chromosomes

  • In eukaryotic cells, DNA is packaged into structures called chromosomes.
  • Each chromosome contains a single, very long DNA molecule and associated proteins.
  • The chromosomes are responsible for the proper segregation of DNA during cell division.

V. Replication

  • Replication is the process by which DNA is copied, allowing it to be passed on to daughter cells during cell division.
  • Replication begins with the unwinding of the double helix and the separation of the two strands.
  • New nucleotides are then added to the single strands, with complementary base pairing ensuring that the new strand is a perfect copy of the original.

VI. Conclusion

  • In conclusion, DNA is a complex and fascinating molecule that plays a crucial role in the biology of all living organisms.
  • Its double helix structure, chemical composition, and ability to replicate make it a vital part of genetics and the study of life.


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