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Hippo Signaling Pathway
The Hippo signaling pathway, initially discovered in Drosophila, plays a pivotal role in regulating organ size by orchestrating cellular processes such as growth, division, and apoptosis. Unlike traditional signaling pathways, Hippo lacks a specific ligand or receptor, instead relying on intricate interactions and key players to govern its intricate cascade. Notably, the loss of Hippo…
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Stem Cells
Delve into the fundamental aspects of the stem cell concept through these study notes. Explore the intricacies of stem cell division, potency variations, and the role of progenitor cells. From totipotent and pluripotent stem cells to the significance of adult stem cells, grasp the essence of these versatile entities that drive cellular diversity and tissue…
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Stem Cell Regulation
Dive into the intricate world of stem cell regulation with these comprehensive study notes. Explore the dynamic interplay between extracellular and intracellular factors that dictate stem cell behavior. From the pivotal role of the stem cell niche to the influence of cytoplasmic determinants, transcriptional networks, and epigenetic patterns, uncover the mechanisms that steer stem cells…
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Pluripotent Stem CellsÂ
Explore the realm of pluripotent stem cells through these insightful study notes. Unveil their significance in research and therapy, their origin in the mammalian inner cell mass, and the intricate regulatory mechanisms that maintain their pluripotency. Delve into the orchestration of gene expression, the roles of key transcription factors, and the interplay of cell-to-cell interactions…
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Gastrulation: The Foundation of Life
Explore the pivotal process of gastrulation in animal development. Learn how cells rearrange to form germ layers, creating the foundation for body structures and axes. Understand the significance of this stage as we delve into movements, axes development, and its crucial role in shaping organisms.
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