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Knock Out and Knock Down Gene
The text discusses the molecular basis of knock out and knock down gene mechanisms, which are powerful tools for studying gene function. It explains how these mechanisms work, the methods used to generate them, and their advantages and disadvantages. The downstream effects of gene disruption can vary depending on the gene and organism being studied,…
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Regulation of Transcription in Eukaryotes
Transcription regulation is a vital process in eukaryotes that enables the control of gene expression. It is achieved through the interaction of various proteins, non-coding regions of DNA, and small non-coding RNAs. Activators, enhancers, silencers, repressors, miRNA-mediated gene silencing, and genetic imprinting are all mechanisms that contribute to this control. Activators increase the rate of…
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Cancer and cell cycle
The article explains the role of the cell cycle in the development of cancer. The cell cycle is a series of events that a cell goes through as it grows and divides into two daughter cells. Disruption in the regulation of the cell cycle can lead to uncontrolled growth and proliferation of cells, causing cancer.…
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Oncogenes and Tumor suppressor genes
The molecular genetics of cancer involves the study of the genetic and molecular changes that occur in cells as they become cancerous. This field of study has led to the identification of two important classes of genes involved in the development of cancer: oncogenes and tumor suppressor genes. Oncogenes promote cell growth and proliferation, while…
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The RAS gene
This text describes the significance of RAS gene mutations in the development and treatment of cancer. RAS genes play a vital role in regulating cell growth, and mutations in these genes can lead to the development of various cancers, including colorectal, lung, and pancreatic cancer. The three main isoforms of the RAS gene – KRAS,…
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