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Pathogen Recognition and Innate Immunity
The excerpt delves into the crucial topics of pathogen recognition and innate immunity. It highlights the significance of the innate immune system as the first line of defense against invading pathogens, explaining the role of pathogen recognition receptors (PRRs) in detecting unique pathogen structures known as pathogen-associated molecular patterns (PAMPs). The innate immune response’s rapid…
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Functions of Complement system
The complement system is a critical component of the innate immune system that plays a vital role in recognizing and eliminating invading pathogens. Composed of more than 30 plasma proteins, the complement system is activated through several different pathways and exerts its effector functions through various mechanisms. These functions include opsonization, recruitment of inflammatory cells,…
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Classical pathway of Complement system
Diagram illustrating the classical pathway of the complement system, with labeled steps including initiation, activation of C1, formation of C3 convertase, amplification of the complement cascade, and formation of membrane attack complex (MAC).
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