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Gamete Fusion and Prevention of Polyspermy in Mammals
In mammals, the side of the sperm head contacts the egg, initiating the acrosome reaction, which releases enzymes and exposes the inner acrosomal membrane. Membrane fusion starts at the equatorial region, aided by actin polymerization extending microvilli from the egg to the sperm.
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Mammalian Fertilization: Translocation
Mammalian fertilization is an intricate process occurring within the female reproductive tract, which actively regulates the transport and maturity of gametes[. The **oocyte-cumulus complex** plays a crucial role, with cumulus cells forming a protective matrix around the oocyte, aiding its transport to the ampulla of the oviduct. **Sperm translocation** involves several mechanisms, including sperm motility,…
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