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Conditional Specification
Explore the fascinating concept of conditional specification in embryonic development, where cell destinies are shaped by interactions with neighboring cells. Unveil the significance of juxtacrine and paracrine factors, as well as mechanical stress, in determining cell fates. Discover how pivotal experiments by pioneers like Wilhelm Roux and Hans Dreisch challenged traditional notions of autonomy. Delve…
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Hippo Signaling Pathway
The Hippo signaling pathway, initially discovered in Drosophila, plays a pivotal role in regulating organ size by orchestrating cellular processes such as growth, division, and apoptosis. Unlike traditional signaling pathways, Hippo lacks a specific ligand or receptor, instead relying on intricate interactions and key players to govern its intricate cascade. Notably, the loss of Hippo…
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