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Knock Out and Knock Down Gene
The text discusses the molecular basis of knock out and knock down gene mechanisms, which are powerful tools for studying gene function. It explains how these mechanisms work, the methods used to generate them, and their advantages and disadvantages. The downstream effects of gene disruption can vary depending on the gene and organism being studied,…
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RNA Interference (RNAi)
The article provides an introduction to RNA interference (RNAi), a process by which the expression of specific genes is regulated at the post-transcriptional level. It explains the biochemistry of siRNA and shRNA, the mechanism of action, and the downstream effects of RNAi. The article also discusses the role of RNAi in cancer treatment and defense…
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