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Chromosomal Sex Determination in Drosophila
Discover the unique chromosomal sex determination in Drosophila, where the intricate interplay of genes and chromosomes orchestrates sex. Dive into the captivating journey of how the X chromosome, Sex-lethal gene, and a cascade of molecular events shape sex-specific traits. Uncover the pivotal roles of transformer, doublesex gene, and transcription factors in steering the course of…
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Regulation of Transcription in Eukaryotes
Transcription regulation is a vital process in eukaryotes that enables the control of gene expression. It is achieved through the interaction of various proteins, non-coding regions of DNA, and small non-coding RNAs. Activators, enhancers, silencers, repressors, miRNA-mediated gene silencing, and genetic imprinting are all mechanisms that contribute to this control. Activators increase the rate of…
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Electrophoretic Mobility Shift Assay: EMSA
The text describes Electrophoretic Mobility Shift Assay (EMSA), a molecular biology technique used to study protein-DNA interactions. EMSA is based on the principle that proteins can bind to specific regions of DNA and alter its conformation, affecting the mobility of the DNA in an electric field. This technique is used to study transcription regulation, DNA…
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